Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1987-12-07
1991-01-08
Griffin, Ronald W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
514927, 568376, 585 20, A61K 3100, C07C 1300
Patent
active
049837230
ABSTRACT:
A cycloalkane derivative represented by the formula (I): ##STR1## wherein A, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, Z, and n are as defined in the specification. The compounds of formula (I) exhibit activities against peptic ulcers and are useful as therapeutic and prophylactic agents for peptic ulcers.
REFERENCES:
patent: 4888417 (1989-12-01), Shiraga et al.
Chemical Abstracts, vol. 85, 1976, p. 480, Abstract No. 176948j.
J. Meinwald et al., "Defense Mechanism of Arthropods: XXV. Stereospecific Synthesis of an Allenic Sesguiterpenoid from the Grasshopper Romalea microptera," Tetrahedron Letters, No. 21, Pergamon Press, 1969, pp. 1657-1660.
A. Haag et al., "2. Synthese von (-)-(R)-4-Hydroxy-Beta-Ionon und (-)-(5R,6S)-5-Hydroxy-4,5-Dihydro-Alpha-Ionen Aus (-)-(S)-Alpha-Ionon", Helvetica Chimica Acta, vol. 63, No. 2.
Fukaya Chikara
Okano Kanemichi
Yasuda Hitoshi
Yokoyama Kazumasa
Green Cross Corporation
Griffin Ronald W.
White Everett
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