Cyclo substituted propyleneamine oxime and its use as a brain im

Details Cyclo substituted propyleneamine oxime and its use as a brain im Cyclo substituted propyleneamine oxime and its use as a brain im

1989-12-20

1991-06-25

Stoll, Robert L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Radioactive metal containing

424 11, 424 9, 422 61, 206569, A61K 4300, C07F 1300

Patent

active

050268295

ABSTRACT:
A useful brain perfusion imaging agent comprises ##STR1## wherein R completes a four or five member ring. The agent is stable in vitro permitting its use up to six to eight hours after preparation.

REFERENCES:
patent: 4615876 (1986-10-01), Troutner et al.
patent: 4714605 (1987-12-01), Feld et al.
patent: 4789736 (1988-12-01), Canning et al.
patent: 4818813 (1989-04-01), Nowotnik et al.
patent: 4895960 (1990-01-01), Deutsch
Hung et al., J. Nucl. Med., 29:1568-1576 (1988).
35th Annual Meeting, J. Nucl. Med., vol. 29, No. 5, May 1988.

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