Cyclo substituted propyleneamine oxime and its use as a brain im

Details Cyclo substituted propyleneamine oxime and its use as a brain im Cyclo substituted propyleneamine oxime and its use as a brain im

1989-01-23

1990-01-23

Lechert, Jr., Stephen J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 88, 549510, 564253, 534 10, 534 14, 424 11, 424 9, A61K 4902, C07D20500, C07D30500, C07C13100

Patent

active

048959600

ABSTRACT:
A useful brain perfusion imaging agent comprises ##STR1## wherein R completes a four or five member ring. The agent is stable in vitro permitting its use up to six to eight hours after preparation.

REFERENCES:
patent: 4615876 (1986-10-01), Troutner et al.
patent: 4789736 (1988-12-01), Canning et al.
patent: 4818813 (1989-04-01), Nowotnik et al.
Hung et al.,: J. Nucl. Med., 29:1568-1576 (1988).
35th Annual Meeting of the J. Nucl. Med., vol. 29, No. 5, May, 1988.

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