Cyclized amino acid derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S358000, C544S359000

Reexamination Certificate

active

06849630

ABSTRACT:
The present invention relates to cyclized amino acid derivatives for treating or preventing neuronal damage associated with neurological diseases. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage.

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Hori, M., et al., “N-(1,2-Diphenylethyl)piperazines,” retrieved from STN Database accession No. 85:33075.
Choi, S.W., et al., “Design, Synthesis, and Biological Evaluation of Novel Non-Piperazine Analogues of 1-[2-(Dephenylmethoxy)ethyl]-and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-)3-phenylpropyl)piperazines as Dopamine Transporter Inhibitors,”J. Med. Chem., 42(18):3647-3656 (1999).
Tsizin, Y.S., et al., “The structure and anthelmintic activity of tricyclic analogs praziquantel and 4-acyl-2-piperazinones,” retrieved frm STN Database accession No. 117:39808.

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