Cyclin E genes and proteins

Details Cyclin E genes and proteins Cyclin E genes and proteins

1998-12-30

2000-12-26

Prouty, Rebecca E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 4352523, 435 6, 536 231, C12P 2106, C12N 1500, C12N 500, C12Q 168, C07H 2102

Patent

active

061657530

ABSTRACT:
Disclosed are nucleic acid molecules encoding novel cyclin E2 polypeptides. Also disclosed are methods of preparing the nucleic acid molecules and polypeptides, and methods of using these molecules.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 4970154 (1990-11-01), Chang
patent: 5011472 (1991-04-01), Aebischer et al.
patent: 5106627 (1992-04-01), Aebischer et al.
patent: 5252714 (1993-10-01), Harris et al.
patent: 5399346 (1995-03-01), Anderson et al.
patent: 5449755 (1995-09-01), Roberts et al.
patent: 5489743 (1996-02-01), Robinson et al.
patent: 5557032 (1996-09-01), Mak
patent: 5593875 (1997-01-01), Wurm et al.
patent: 5631236 (1997-05-01), Woo et al.
patent: 5635399 (1997-06-01), Kriegler et al.
patent: 5645999 (1997-07-01), Roberts et al.
patent: 5653975 (1997-08-01), Baetge et al.
patent: 5672344 (1997-09-01), Kelly et al.
patent: 5676954 (1997-10-01), Brigham
patent: 5679559 (1997-10-01), Kim et al.
patent: 5688665 (1997-11-01), Massague et al.
Ausubel et al., eds., Current Protocols in Molecular Biology, Green Publishers Inc. and Wiley and Sons, NY (1994) (Table of contents provided).
Ausubel et al., eds., "Metal-Chelate Affinity Chromatography", Current Protocols in Molecular Biology, Section 10.11.8, John Wiley & Sons, NY (1993).
Chevalier et al., "Xenopus cyclin E, a nuclear phosphoprotein, accumulates when oocytes gain the ability to initiate DNA replication", J. Cell Sci., 109: 1173-1184 (1996).
Coats et al., "23 Cell cycle regulation", Signal Transduction, Heldin and Purton, eds., Chapman and Hall, publishers, 347-360 (1996).
Cook, "Scintillation proximity assay: a versatile high-throughput screening technology", Drug Discovery Today, 1: 287-294 (1996).
Damjanov et al., "Molecular Cloning and Characterization of Murine Cyclin E#", Biochem. Biophys. Res. Comm., 201: 994-1000 (1994).
Dayhoff et al., Atlas of Protein Sequence and Structure, 5, supp. 3 (1978) (Table of contents provided).
Diehl et al., "A Dominant-Negative Cyclin D1 Mutant Prevents Nuclear Import of Cyclin-Dependent Kinase 4 (CDK$) and its Phosphorylation by CDK-Activating Kinase", Mol. Cell. Biol., 17: 7362-7374 (1997).
Engels et al., "Gene Synthesis", Angew. Chem. Intl. Ed., 28: 716-734 (1989).
Eppstein et al., "Biological activity of liposome-encapsulated murine interferon .gamma. is mediated by a cell membrane receptor", Proc. Natl. Acad. Sci. USA, 82: 3688-3692 (1985).
Francis, "Protein modification and fusion proteins", Focus on Growth Factors, 3: 4-10 (1992).
Genbank Accession number R84331.
Gennaro, ed., Remington's Pharmaceutical Sciences, 18.sup.th Edition, Mack Publishing Company (1990) (Table of contents provided).
Gray-Bablin et al., "Cyclin E, a redundant cyclin in breast cancer", Proc. Natl. Acad. Sci USA, 93: 15215-15220 (1996).
Gudas et al., "Nuclear posttranscriptional processing of thymidine kinase mRNA at the onset of DNA synthesis", Proc. Natl. Acad. Sci. USA, 85: 4705-4709 (1988).
Harlow et al., eds., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY p. 49 (1998).
Houghten et al., "General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids", Proc Natl Acad. Sci. USA, 82: 5132 (1985).
Kitts et al., "A Method for Producing Recombinant Baculovirus Expression Vectors at High Frequency", Biotechniques, 14: 810-817 (1993).
Koff et al., "Human Cyclin E, a New Cyclin That Interacts with Two Members of the CDC2 Gene Family", Cell, 66: 1217-1228 (1991).
Langer, et al., "Biocompatibility of polymeric delivery systems for macromolecules", J. Biomed. Mater. Res., 15: 167-277 (1981).
Langer, "Controlled release of macromolecules", Chem. Tech., 12: 98-105 (1982).
Lauper et al., "A New G1-Specific Cyclin in Mammalian Cells", Abstracts from the 1998 Cold Spring Harbor Laboratory Cell Cycle Meeting, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p. 115 (1998).
Lees, "Cyclin dependent kinase regulation", Curr. Opinions Cell Biol., 7: 773-780 (1995).
Lucklow et al., "Efficient Generation of Infectious Recombinant Baculoviruses by Site-Specific Transposon-Mediated Insertion of Foreign Genes into a Baculovirus Genome Propagated in Escherichia coli", J. Virol., 67: 4566-4579 (1993).
Lucklow, "Baculovirus systems for the expression of human gene products", Curr. Opin. Biotechnol., 4: 564-572 (1993).
Marston et al., "Solubilization of Protein Aggregates", Meth. Enz., 182: 264-275 (1990).
Merrifield et al., "Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide", J. Am. Chem. Soc., 85: 2149 (1963).
Mumberg et al., "Cyclin E, a new splice variant of human cyclin E with a unique expression pattern during cell cycle progression and differentiation", Nuc. Acids Res., 25: 2098-2105 (1997).
Ninomiya-Tsuji et al., "Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation", Proc. Natl. Acad. Sci. USA, 88: 9006-9010 (1991).
O'Reilly et al., "Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth", Cell, 88: 277-285 (1997).
Ohtsubo et al., "Human Cyclin E, a Nuclear Protein Essential for the G.sub.1 -to-S Phase Transition", Mol. Cell. Biol., 15: 2612-2624 (1995).
Polyak et al., "Cloning of p27.sup.kp1, a Cyclin-Dependent Kinase Inhibitor and a Potential Mediator of Extracellular Antimitogenic Signals", Cell, 78: 59-66 (1994).
Porter et al., "Expression of cell-cycle regulators p27.sup.kp1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients", Nature Med., 3: 222-225 (1997).
Prosite Accession Number PS00292.
Richardson et al., "A Drosophila G.sub.1 -specific cyclin E homolog exhibits different modes of expression during embryogenesis", Development, 119: 673-690 (1993).
Sambrook et al., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1989) (Table of contents provided).
Sarcevic et al., "Differential Phosphorylation of T-47D Human Breast Cancer Cell Substrates by D1-, E-, and A-type Cyclin-CDK Complexes", J. Biol. Chem., 272: 33327-33337 (1997).
Sheaff et al., "Cyclin E-CDK2 is a regulator of p27.sup.Kp1 ", Genes and Devel., 11: 1464-1478 (1997).
Sherr et al., "Inhibitors of mammalian G, cyclin-dependent kinases", Genes and Devel., 9: 1149-1163 (1995).
Sherr, "Cancer Cell Cycles", Science, 274: 1672-1677 (1996).
Sidman et al., "Controlled Release of Macromolecules and Pharmaceuticals from Synthetic Polypeptides Based on Glutamic Acid", Biopolymers, 22: 547-556 (1983).
Stewart and Young, Solid Phase Peptide Synthesis, Pierce Chemical Co., Rockford, IL (1984) (Table of contents provided).
Tsai et al., "Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase", Nature, 353: 174-177 (1991).
Turner et al., "Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate", Genes and Devel., 8: 1434-1447 (1994).
Yarden et al., Devel. Dynam, 206: 1-11 (1996).
Zariwala et al., "Human Cyclin E2 Represents a Novel E-type Cyclin", Pathways to Cancer, Cold Spring Harbor Winter Conference.

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