Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1998-02-05
1999-10-19
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
435325, 4352523, 4353201, 536 232, C12P 2106, C12N 510, C12N 120, C07H 2104
Patent
active
059688009
ABSTRACT:
An isolated nucleic acid molecule is disclosed which encodes a novel human cyclin-dependent kinase (CDK) which comprises a novel cyclin binding domain signature sequence and lacks several heretofore conserved amino acid residues involved in regulation of the cdk/cyclin complex. Associated proteins and biologically active mutant forms are also disclosed.
REFERENCES:
Brabbilla and Draetta. Oncogene, 9, 3037-3041, Sep. 1994.
Hand J. Mark
Merck & Co. , Inc.
Monshipouri M.
Tribble Jack L.
Wax Robert A.
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