Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides
Patent
1994-09-19
1997-10-14
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Cyclic peptides
530318, 530324, 930170, 930270, 930DIG546, 930DIG548, C07K 760
Patent
active
056774192
ABSTRACT:
Analogs of porcine Vasoactive Intestinal Peptide are disclosed. The analogs have been cyclized by the covalent attachment, via an amide bond, of the side-chain carboxy terminus of one amino acid in the peptide chain to the side-chain amino terminus of another amino acid in the peptide chain. The claimed compounds are useful for the treatment of asthma.
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Bolin David Robert
O'Donnell Margaret
Chan Christina Y.
Hoffmann-La Roche Inc.
Johnston George W.
Pokras Bruce A.
Tramaloni Dennis P.
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