Cyclic urea HIV protease inhibitors

Details Cyclic urea HIV protease inhibitors Cyclic urea HIV protease inhibitors

1996-03-11

1997-11-04

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540492, C07D24304, A61K 3155

Patent

active

056839995

ABSTRACT:
This invention relates to substituted cyclic ureas and derivatives thereof, including compounds of formula (II): ##STR1## said compounds being useful as inhibitors of HIV protease. The present invention also relates to pharmaceutical compositions comprising such compounds and to method of using these compounds for the treatment HIV infection. The present invention also relates to the use of such compounds in processes for the identification of HIV protease inhibitors and for the inhibition or detection of HIV in a bodily fluid sample.

REFERENCES:
Lam et al., Science (1994) 263:380-384.

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