Cyclic tetrapeptide and process for preparing the same

Details Cyclic tetrapeptide and process for preparing the same Cyclic tetrapeptide and process for preparing the same

1990-06-12

1992-05-12

Chan, Christina

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

435 711, 930270, 930DIG781, C07K 512

Patent

active

051129442

ABSTRACT:
A cyclic tetrapeptide having the formula (I): ##STR1## wherein n is 4 or 3 and a process for preparing the above cyclic tetrapeptide. The cyclic tetrapeptide of the present invention inhibits transformation of cells caused by oncogenes and possesses activities for recovering to a normal cell and for inhibiting proliferation of carcinoma cells. Therefore, the cyclic tetrapeptide of the present invention is useful for an active ingredient of an antitumor agent.

REFERENCES:
patent: 4737487 (1988-04-01), Watts et al.
Lehninger, Principles of Biochemistry, Worth Publishers, Inc., pp. 95-117 (1982).
"Studies on WF-3161, A New Antitumor Antibiotic", The Journal of Antibiotics, vol. 36 (1983), pp. 478-483, Kazuyoshi Umehara et al.

Affiliated with

Also associated with

Rating

Cyclic tetrapeptide and process for preparing the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic tetrapeptide and process for preparing the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic tetrapeptide and process for preparing the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2426434