Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-04-05
2005-04-05
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S432000, C514S445000, C514S446000, C514S448000, C549S009000, C549S013000, C549S028000, C549S072000, C546S156000
Reexamination Certificate
active
06875790
ABSTRACT:
The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease.
REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4857507 (1989-08-01), Rosenberg et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5484926 (1996-01-01), Dressman
patent: 5514801 (1996-05-01), Bertenshaw et al.
patent: 5824688 (1998-10-01), Kalish
patent: 5827858 (1998-10-01), Kalish
patent: 5827859 (1998-10-01), Kalish
patent: 5827891 (1998-10-01), Kalish
patent: 5849784 (1998-12-01), Bertenshaw et al.
patent: 6265583 (2001-07-01), Bertenshaw et al.
patent: 6552203 (2003-04-01), Bertenshaw et al.
patent: 7982387 (1988-04-01), None
patent: 0114993 (1984-08-01), None
patent: 172347 (1986-02-01), None
patent: 223437 (1987-05-01), None
patent: 0264795 (1988-04-01), None
patent: 0104041 (1988-07-01), None
patent: 337714 (1989-10-01), None
patent: 0342541 (1989-11-01), None
patent: 0346847 (1989-12-01), None
patent: 356223 (1990-02-01), None
patent: 289898 (1990-10-01), None
patent: 389898 (1990-10-01), None
patent: 393445 (1990-10-01), None
patent: 393457 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 2184730 (1987-07-01), None
patent: 2200115 (1988-07-01), None
patent: 2209752 (1989-05-01), None
patent: WO 8403044 (1984-08-01), None
patent: WO 9200750 (1992-01-01), None
Roberts et al., “Rational Design of Peptide-Based Proteinase Inhibitors”,Science, 248, 358 (1990).
Erickson et al., “Design Activity and 2.8A Crystal Structure of C2Symmetric Inhibitor Complexed to HIV-1 Protease”,Science, 249, 527 (1990).
Pearl et al., “Sequence specificity of Retroviral Protease”,Nature, vol. 328, No. 6130, Aug. 6-12, 1987, p. 482.
Martin, Drugs of the Future, 1991 16(3), 210-212.
Meek et al., “Inhibition of HIV-1 Protease in Infected T-lymphocytes by Synthetic Peptide Analogues”,Nature, 343, 90 (1990.
McQuade et al., “A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle Maturation”,Science, 274, 454-456 (1990).
D.H. Rich and V.J. Hunby; Dept. Struct. Funct. Proc. Am. Peptide Inhibitors of Protease Sym. 8thed., pp. 511-520 (1983).
Rosenberg et al.,J. Med. Chem., 30, 1224-1228 (1987).
U.S. patent application Ser. No. 07/789,646 by John J. Talley et al., filed Nov. 14, 1991, entitled “Retroviral Protease Inhibitors” (07-21(807)A).
U.S. patent application Ser. No. 07/789,645 by John J. Talley et al., filed Nov. 14, 1991, entitled “Retroviral Protease Inhibitors” (07-21(829)A).
U.S. patent application Ser. No. 07/789,644 by John J. Talley et al., filed Nov. 14, 1991, entitled “Retroviral Protease Inhibitors” (07-21(831)A).
U.S. patent application Ser. No. 07/789,642 by John J. Talley et al., filed Nov. 14, 1991, entitled “Retroviral Protease Inhibitors” (07-21(827)A).
U.S. patent application Ser. No. 07/789,643 by John J. Talley et al., filed Nov. 14, 1991, entitled “Retroviral Protease Inhibitors” (07-21(830)A).
U.S. patent application Ser. No. 07/886,556 by John J. Talley et al., filed May 20, 1992, entitled “Retroviral Protease Inhibitors” (2-2709/1).
U.S. patent application Ser. No. 07/886,663 by John J. Talley et al., filed May 20, 1992, entitled “Retroviral Protease Inhibitors” (2-2710/1).
U.S. patent application Ser. No. 07/886,531 by John J. Talley et al., filed May 20, 1992, entitled “Retroviral Protease Inhibitors” (2-2711/1).
U.S. patent application Ser. No. 07/886,547 by John J. Talley et al., filed May 20, 1992, entitled “Retroviral Protease Inhibitors” (2-2712/1).
U.S. patent application Ser. No. 07/886,700 by John J. Talley et al., filed May 20, 1992, entitled “Retroviral Protease Inhibitors” (07-21(879A).
U.S. patent application Ser. No. 07/935,071 by Michael Vazquez et al., filed Aug. 25, 1992, entitled Sulfonylakanoylamino Hydroxyethylamino Sulfonamides Useful as Retroviral Protease Inhibitors (C-2703).
U.S. patent application Ser. No. 07/935,490 by Michael Vazquez et al., filed Aug. 25, 1992, entitled Succinoylamino Hydroxyethylamino Sulfonamides Useful as Retroviral Protease Inhibitors (C-2704).
U.S. patent application Ser. No. 07/934,984 by Michael Vazquez et al., filed Aug. 25, 1992, entitled α- and β-amino Acid Hydroxyethylamino Sulfonamides Useful as Retroviral Protease Inhibitors (C-2705).
U.S. patent application Ser. No. 07/969,683 by Michael Vazquez et al., filed Oct. 30, 1992, entitled Succinolyamino Hydroxyethylamino Sulfamic Acids Useful as Retroviral Protease Inhibitors (C-2741).
U.S. patent application Ser. No. 07/969,612 by Michael Vazquez et al., filed Oct. 30, 1992, entitled Sulfonylakanoylamino Hydroxyethylamino Sulfamic Acids Useful Acids Useful as Retroviral Protease Inhibitors (C-2742).
U.S. patent application Ser. No. 07/968,712 by Michael Vazquez et al., filed Oct. 30, 1992, entitled α- β-Amino Acid Hydroxyethylamino Sulfony Urea Derivatives Useful as Retroviral Protease Inhibitors (C-2751).
U.S. patent application Ser. No. 07/969,616 by Michael Vazquez et al., filed Oct. 30, 1992, entitled Sulfonylalkanoylamino Hydroxyethylamino Sulfonyl Urea Derivatives Useful as Retroviral Protease Inhibitors (C-2752).
U.S. patent application Ser. No. 07/969,682 by Michael Vazquez et al., filed Oct. 30, 1992, entitled Succinolyamino Hydroxyethylamino Sulfonyl Urea Derivatives Useful as Retroviral Protease Inhibitors (C-2753).
U.S. patent application Ser. No. 07/968,730 by Michael Vazquez et al., filed Oct. 30, 1992, entitled α- β-Amino Acid Hydroxyethylamino Sulfamic Acid Derivatives Useful as Retroviral Protease Inhibitors (C-2740).
Bertenshaw Deborah E.
Chrusciel Robert Alan
Clare Michael
Getman Daniel
Heintz Robert M.
Banner & Witcoff , Ltd.
G. D. Searle & Co.
Pharmacia Corporation (Monsanto Corporation)
Seaman D. Margaret
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