Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1982-07-26
1984-10-09
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 41, 536 179, 536 181, 536123, 2601125R, C07H 1526, C07C10352
Patent
active
044762992
ABSTRACT:
New compounds of the following general formula: ##STR1## wherein R.sub.1 is acyl, alkyl, cycloalkyl, carboxyalkyl or ester thereof, heterocyclic group, saccharide residue or hydrogen atom, R.sub.2 stands for hydrogen atom or a lower alkyl and R.sub.3 represents hydrogen atom or a nitrogen-containing group,
are provided, among these, some of the compounds to be isolated and purified from a plant belonging to Genus Rubia, other compounds being prepared by chemically modifying the isolated compounds with various kind of substituents and these new compounds having therapeutic effect, in particular such as antineoplastic, emetic, anorexigenic, psychotropic, vasoconstrictive, papaverinic, antiperkinsonian and/or antidiuretic effect.
REFERENCES:
patent: 3598865 (1971-08-01), Lew
patent: 3978041 (1976-08-01), Jaeggi et al.
Fieser et al., Organic Chemistry, 2nd Ed., Boston: D. C. Heath and Company, 1950, pp. 138, 667-668.
March, Advanced Organic Chemistry, N.Y.: McGraw-Hill Book Company, 1977, pp. 474, 820.
Brown Johnnie R.
Peselev Elli
Tobishi Pharmaceutical Co., Ltd.
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