Cyclic phosphamide derivatives

Details Cyclic phosphamide derivatives Cyclic phosphamide derivatives

1976-11-02

1978-04-18

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260953, 260956, 424303, C07C14368, A61K 31255

Patent

active

040851281

ABSTRACT:
Cyclic phosphamide derivatives of the general formula: ##STR1## [wherein X represents a halogen atom, Y represents a lower alkanesulfonyloxy, and R represents a lower alkyl] being useful as medicaments exhibiting antitumor and immunosuppressive activities.

REFERENCES:
patent: 3828090 (1974-08-01), Arnold et al.
Brock et al., Areneim-Forsch (Drug Res.) 24(8), 1139 (1974).
Takamizawa et al., J. Med. Chem., 17, 1237 (1974).
Takamizawa et al. (I), J. Amer. Chem. Soc., 95, 985 (1973).
Takamizawa et al. (II), Tetrahedron Letters, No. 6, 517 (1974).

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