Cyclic phenylsulphinyl-amidine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544335, C07D23322, C07D23906

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active

041074386

ABSTRACT:
Phenylsulphinyl derivatives of the formula ##STR1## in which R.sub.1 represents hydrogen or one or more identical or different substituents, Alk represents a C.sub.2 -C.sub.4 hydrocarbon radical with a linear or branched chain, and A represents C(.dbd.NH)NH.sub.2, C(.dbd.NH)NHOH, C(.dbd.O)NHOH, or ##STR2## where Z is CH.sub.2 CH.sub.2 or CH.sub.2 CH.sub.2 CH.sub.2 and R is H, CH.sub.2 COOH, CH(CH.sub.3)COOH or C(CH.sub.3).sub.2 COOH, and their addition salts, have interesting therapeutic properties on the central nervous system as anxiolytic agents and/or analgesic and anti-inflammatory agents.

REFERENCES:
patent: 3441560 (1969-04-01), Zimmermann
patent: 3551417 (1970-12-01), Symon et al.
Hoff et al., Chem. Abst. 1972, vol. 76, No. 72513m.
Protiva et al., Chem. Abst. 1948, vol. 42, columns 8188-8189.
Walker Chem. Abst. 1976, vol. 84, No. 2,514,833.

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