Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-05-16
2006-05-16
Campell, Bruce R. (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S011400
Reexamination Certificate
active
07045504
ABSTRACT:
The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
REFERENCES:
patent: WO 97 12905 (1997-04-01), None
patent: WO 98 21230 (1998-05-01), None
patent: WO 98 46632 (1998-10-01), None
Sato S, et al, “High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread,” FEBS Lett Sep. 25, 2002:528(1-3):212-6.
Magdolen V et al.: Systematic Mutational Analysis of the Receptor-Binding Region of the Human Urokinase-Type Plasminogen Activator European Journal of Biochemistry, DE, Berlin, vol. 237, 1996, pp. 743-751.
Sato et al., “High-affnity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread”, FEBS Letters 528 (2002), 212-216.
Buergle Markus
Kessler Horst
Potthoff Nils
Schmiedeberg Niko
Wilhelm Olaf
Campell Bruce R.
Heard Thomas S.
Rothwell Figg Ernest & Manbeck
Wilex AG
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