Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1984-01-31
1986-11-04
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514806, 530311, A61K 3724, C07K 726
Patent
active
046210733
ABSTRACT:
The invention relates to cyclic hexapeptides of the general formula III ##STR1## in which X represents the radical of an L-aminoacid of the general formula IIIa ##STR2## in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturated or aromatic monocyclic or bicyclic structure having 3 to 6 carbon atoms, n denotes 0 or 1, and Y represents an aliphatic or aromatic L-aminoacid the side chain of which can be hydroxylated, and their salts with physiologically tolerated acids, and to a process for their preparation and their use and their intermediates.
REFERENCES:
patent: 4235886 (1980-11-01), Freidinger et al.
patent: 4303583 (1981-12-01), Kim et al.
patent: 4310518 (1982-01-01), Freidinger et al.
Veber et al., Nature, 292, 55-58 (1981).
Friedrich Axel
Geiger Rolf
Konig Wolfgang
Sandow Jurgen K.
Teetz Volker
Hoechst Aktiengesellschaft
Phillips Delbert R.
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