Cyclic peptide and method of use for inducing an immunological r

Details Cyclic peptide and method of use for inducing an immunological r Cyclic peptide and method of use for inducing an immunological r

1987-11-23

1988-10-18

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530326, A61K 3702, C07K 708, C07K 710

Patent

active

047787848

ABSTRACT:
A composition for eliciting production of antibody to hepatitis B surface antigen and method of neutralizing the infectivity of hepatitis type B virus. A cyclic polypeptide is prepared having a disulfide bond in a hydrophilic region, namely residues 117-137 or 122-137 and an amino acid sequence unique from that associated with the native 25,000 molecular weight polypeptide derived from hepatitis B surface antigen.

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