Cyclic peptide analogs of somatostatin

Details Cyclic peptide analogs of somatostatin Cyclic peptide analogs of somatostatin

1995-12-26

1998-01-13

Hill, Jr., Robert J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Somatostatin ; related peptides

530328, 930160, C07K 700

Patent

active

057081352

ABSTRACT:
A cyclic peptide analog of somatostatin wherein a disulfide bond links the N-terminus residue and the C-terminus residue.

REFERENCES:
patent: 4133782 (1979-01-01), Vale, Jr. et al.
patent: 4211693 (1980-07-01), Rivier et al.
patent: 4428942 (1984-01-01), Rivier et al.
patent: 4798821 (1989-01-01), Hartmann
patent: 4853371 (1989-08-01), Coy et al.
patent: 5358934 (1994-10-01), Borovsky et al.
patent: 5506339 (1996-04-01), Coy et al.
Fisher et al., "Somatostatin Analog: Plasma Catecholamine Suppresion Mediated by the Central Nervous System" Endocrinology 107:714-718, 1980.
Vale et al., "Biologic and Immunologic Activities and Applications of Somatostatin Analogs", Metabolism 27, No. 9, Suppl. 1, pp. 1391-1401, 1978.
Veber et al., "Highly Active Cyclic and Bicyclic Somatostatin Analogues of REduced Ring Size", Reprint from Nature 280:512-514, 1979.

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