Cyclic pentapeptides displaying somatostatin antagonism and meth

Details Cyclic pentapeptides displaying somatostatin antagonism and meth Cyclic pentapeptides displaying somatostatin antagonism and meth

1983-06-06

1985-03-19

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

2601125R, 2601125S, C07C10352, A61K 3702

Patent

active

045058970

ABSTRACT:
Novel cyclic pentapeptide somatostatin antagonists and method for increasing the release of growth hormone, insulin, and glucagon in mammals are described.

REFERENCES:
patent: 4235886 (1980-11-01), Freidinger et al.
Chemical Abstracts, 80, 460, (1974), Abst. No. 83616f.
Chemical Abstracts, 97, 876, (1982), Abst. No. 182876y.
Bach et al., J. Am. Chem. Soc., 104, No. 2, 572-576, (1982).
Parsons, Peptide Hormones, University Park Press, Baltimore.
Nutt et al., Int. J. Pept Protein Res., 21(1), 66-73, (1983).

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