Cyclic pentapeptides and their preparation

Details Cyclic pentapeptides and their preparation Cyclic pentapeptides and their preparation

2006-05-30

2006-05-30

Campell, Bruce R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S317000

Reexamination Certificate

active

07053047

ABSTRACT:
This invention relates to cyclic peptides, with the following formula (I) (SEQ ID NO: 1),in-line-formulae description="In-line Formulae" end="lead"?cyclo(Xaa-Arg-Pro-Ala-Lys)  (I)in-line-formulae description="In-line Formulae" end="tail"?where Xaa is Ala, Gly, Glu, Gln, Asp, Asn, Arg or Lys. The cyclic peptides have thrombolytic effects. This invention also relates to cyclic peptide preparations.

REFERENCES:
patent: 5514590 (1996-05-01), Garvin et al.
patent: WO 00/75176 (2000-12-01), None
Yin-Ye Wang, Ming Zhao, Shi-Qi Peng, Chang-Ling Li, Qin-Lu Zhou and Qiang Li, “The Antithrombotic Effects of P6A and its Derivatives”, Journal of Chinese Pharmaceutical Sciences 1996, 5 (4), pp. 174-176.

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