Cyclic neurokinin A antagonists

Details Cyclic neurokinin A antagonists Cyclic neurokinin A antagonists

1997-03-05

1998-03-24

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 17, 530317, 530329, A61K 3812, C07K 500, C07K 700

Patent

active

057312869

ABSTRACT:
Antagonists of neurokinin A which are derivatives of naturally occurring neurokinin A in which the amide bond connecting the two amino acids on the carboxy terminal end is modified are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.

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