Cyclic imides as H.sub.1 -antagonists

Details Cyclic imides as H.sub.1 -antagonists Cyclic imides as H.sub.1 -antagonists

1986-12-02

1988-10-11

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544361, 544362, 544372, 544373, 544403, 546 15, 546 16, 546 76, 546 79, 546 97, 546183, 546200, 546272, 546273, 548424, C07D40306

Patent

active

047772549

ABSTRACT:
Polycyclic 1,3-dione imides N-alkylated with variously N-substituted alkyl- or cycloalkyl amines afford histamine H.sub.1 -receptor antagonists of the formula ##STR1## wherein R is polycyclic alkyl moiety;

REFERENCES:
patent: 3398051 (1968-08-01), Wu
patent: 4006233 (1977-02-01), Shepard et al.
patent: 4261990 (1981-04-01), Bowman
patent: 4423049 (1983-12-01), Temple
patent: 4435419 (1984-03-01), Epstein et al.
patent: 4507303 (1985-03-01), Ishizumi et al.
patent: 4524206 (1985-06-01), New et al.
patent: 4562255 (1985-12-01), Freed et al.
patent: 4598078 (1986-07-01), Ishizumi et al.
Wu et al., J. Med. Chem. p. 876 (1969).

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