Cyclic imide thione activated polyalkylene oxides

Details Cyclic imide thione activated polyalkylene oxides Cyclic imide thione activated polyalkylene oxides

1994-08-29

1995-04-11

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Solid synthetic organic polymer

514 2, 514 4, 514 8, 514772, 5147721, 5147727, 514773, 514777, 514785, 514788, 514950, 514 42, 514 44, 435174, 435177, 435180, 435181, 435188, 4241781, 424 942, 424 943, A01N 2500, A61K 4700

Patent

active

054058775

ABSTRACT:
Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

REFERENCES:
patent: 4492657 (1985-01-01), Heiss
patent: 4495355 (1985-01-01), Fujita et al.
patent: 5122614 (1992-06-01), Zalipsky
patent: 5321095 (1994-01-01), Greenwald
Chemical Abstracts 112(14): 129084r.

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