Cyclic hydroxamic acid as metalloproteinase inhibitors

Details Cyclic hydroxamic acid as metalloproteinase inhibitors Cyclic hydroxamic acid as metalloproteinase inhibitors

2005-02-22

2005-02-22

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S330000, C514S346000, C514S613000, C546S153000, C546S225000, C546S298000, C564S163000

Reexamination Certificate

active

06858626

ABSTRACT:
The present application describes novel cyclic hydroxamic acids of formula I:or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NRa, and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease inhibitors.

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