Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-03-28
2011-12-13
Bradley, Christina (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S019300, C514S019400, C514S019500, C514S021100
Reexamination Certificate
active
08076287
ABSTRACT:
The present invention provides cyclic hexadepsipeptides and their pharmaceutically acceptable salts, solvates and prodrugs, and methods for obtaining the compounds, by fermentation, optionally followed by post-biosynthesis chemical modification. The present invention further provides uses of cyclic hexadepsipeptides, and their pharmaceutically acceptable salts, solvates and prodrugs as pharmaceuticals, in particular to their use as antibacterial, antifungal or antineoplastic agents, and to pharmaceutical compositions comprising a cyclic hexadepsipeptide, or a pharmaceutically acceptable salt, solvate or prodrug thereof, together with a carrier.
REFERENCES:
patent: 0 995 758 (2000-04-01), None
Tajiri et al, Amylase Inhibitors Produced by Streptomyces-SP No. 280, Agricultural and Biological Chemistry, vol. 47, No. 4, 1983, pp. 671-680.
Banskota Arjun H.
McAlpine James B.
Piraee Mahmood
Zazopoulos Emmanuel
Bradley Christina
Roylance Abrams Berdo & Goodman L.L.P.
Thallion Pharmaceuticals Inc.
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