Cyclic heptapeptide anti-inflammatory agent

Details Cyclic heptapeptide anti-inflammatory agent Cyclic heptapeptide anti-inflammatory agent

1994-02-18

1995-08-22

Lilling, Herbert J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530317, 530321, A61K 3812, A61K 3800

Patent

active

054440432

ABSTRACT:
A cyclic heptapeptide anti-inflammatory agent named cyclomarin-A is disclosed.
Cyclomarin-A is produced by a specific marine actinomycete. The cyclomarin-A producing bacterium is isolated from sediment located in marine estuaries in and around San Diego, Calif. Fermentation of the isolated bacterium in saltwater-based media produces cyclomarin-A as a secondary by-product. The cyclomarin-A is useful as an anti-inflammatory agent.

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patent: 5294603 (1994-03-01), Rinehart
patent: 5336757 (1994-08-01), Gulavita et al.

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