Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materi

Details Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materi Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materi

1994-05-27

1997-12-30

Prouty, Rebecca E.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 691, 4351723, 4353201, 4352523, 435325, C12N 916, C12N 1555

Patent

active

057029369

ABSTRACT:
The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.

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