Cyclic dodecapeptide analogs of somatostatin and intermediates

Details Cyclic dodecapeptide analogs of somatostatin and intermediates Cyclic dodecapeptide analogs of somatostatin and intermediates

1975-06-16

1976-12-28

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

260 78A, 2601125S, A61K 3700, C07C10352

Patent

active

040002594

ABSTRACT:
Cyclic dodecapeptide analogs of somatostatin without cysteine amino acid residues and intermediates obtained in the synthesis of such compounds are described. These cyclic dodecapeptides inhibit the secretion of glucagon and hence have application in the treatment of diabetes mellitus.

REFERENCES:
patent: 3917581 (1975-11-01), Immer et al.

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