Cyclic di-guanylate metabolic enzymes

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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435 691, 435 711, 435170, 435199, 435232, 4353201, 935 9, 935 11, 935 66, 935 72, 935 73, 536 231, 536 232, 536 237, C12N 1563, C12N 1570, C12N 1574, C12P 104

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057598282

ABSTRACT:
The present invention provides the nucleotide sequences of Acetobacter operons, cdg operons encoding genes for the biosynthesis and degradation of cyclic diguanosine monophosphate (c-di-GMP). Specifically, the nucleotide sequences and deduced amino acid sequences of 3 phosphodiesterases isozymes, 3 diguanylate cyclase isozymes, and 2 polypeptides of unidentified function are provided. Also provided for are various strains of microorganisms, including Acetobacter cells genetically manipulated so as to produce elevated and/or reduced levels of one or more cdg operon encoded proteins.

REFERENCES:
patent: 5001230 (1991-03-01), Brown et al.
Ross, et al., Nature, 325:279-281 (1987).
Ross, et al., Microbiological Reviews 55(1):35-58 (1991).
Ross, et al., The Journal of Biological Chemistry 265:18933-18943 (1990).
Ross, et al., FEBS Letters 186:191-196 (1985).
Benziman and Palgi, Journal of Bacteriology 104:211-218 (1970).
Ross, et al., Carbohydrate Research 149:101-117 (1986).
Abstract of Papers: American Chemical Society A. Ben-Bassat, et al., "Genetic Engineering Methods to Increase Cellulose Volumetric Productivity and Yield in ACETOBACTER xylinum", vol. 203, No. 1-3, Apr. 1992.
Bailey, J. E. (1991) Toward A Science of Metabolic Engineering, Science, vol. 252, pp. 1668-1675.
Walsh, K.A. et al. (1981) Advances in Protein Sequencing in "Annual Review of Biochemistry," vol. 50, pp. 261-284. (Annual Reviews, Inc., Palo Alto, CA).
Lathe, R. (1985) Journal of Molecular Biology, vol. 183, pp. 1-12.
Shatzman, A. R. et al. (1987) in "Methods in Enzymology", vol. 152, pp. 661-673, (Academic Press, San Diego, CA).

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