Cyclic derivatives as modulators of chemokine receptor activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S224000

Reexamination Certificate

active

07572813

ABSTRACT:
The present application describes modulators of MCP-1 of formula (I):or pharmaceutically acceptable salt forms thereof, useful for the prevention of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.

REFERENCES:
patent: 4851423 (1989-07-01), Girijavallabhan et al.
patent: 5272167 (1993-12-01), Girijavallabhan et al.
patent: 5710171 (1998-01-01), Dinsmore et al.
patent: 5770620 (1998-06-01), Mjalli et al.
patent: 5968965 (1999-10-01), Dinsmore et al.
patent: 5981491 (1999-11-01), Baxter et al.
patent: 6011052 (2000-01-01), Padia et al.
patent: 6028087 (2000-02-01), Bondinell et al.
patent: 6030946 (2000-02-01), Klaus et al.
patent: 6048861 (2000-04-01), Askew et al.
patent: 6084065 (2000-07-01), Cammaggi et al.
patent: 6100423 (2000-08-01), Collins et al.
patent: 6162790 (2000-12-01), Bemis et al.
patent: 6706712 (2004-03-01), Cherney
patent: 6974836 (2005-12-01), Cherney et al.
patent: 2003/0216434 (2003-11-01), Cherney
patent: 2004/0186140 (2004-09-01), Cherney et al.
patent: 2004/0186143 (2004-09-01), Carter et al.
patent: 2004/0235835 (2004-11-01), Carter
patent: 2004/0235836 (2004-11-01), Cherney
patent: 2005/0043392 (2005-02-01), Carter et al.
patent: 2005/0054626 (2005-03-01), Carter et al.
patent: 2005/0054627 (2005-03-01), Carter et al.
patent: 2005/0065147 (2005-03-01), Carter et al.
patent: 2005/0282882 (2005-12-01), Cherney et al.
patent: 0264795 (1987-10-01), None
patent: 0560407 (1987-12-01), None
patent: 0731107 (1996-02-01), None
patent: 377869 (1991-03-01), None
patent: 93/15047 (1993-08-01), None
patent: 94/03479 (1994-02-01), None
patent: 94/20062 (1994-09-01), None
patent: 96/22966 (1996-08-01), None
patent: 97/00894 (1997-01-01), None
patent: 98/06703 (1998-02-01), None
patent: 99/07351 (1999-02-01), None
patent: 99/07678 (1999-02-01), None
patent: 99/17790 (1999-04-01), None
patent: 99/25686 (1999-05-01), None
patent: 99/40913 (1999-08-01), None
patent: 99/40914 (1999-08-01), None
patent: 97/44329 (1999-11-01), None
patent: 00/42071 (2000-07-01), None
patent: 00/46196 (2000-08-01), None
patent: 00/69815 (2000-11-01), None
patent: 00/69820 (2000-11-01), None
patent: WO02/0250019 (2002-06-01), None
patent: WO02/060859 (2002-08-01), None
patent: WO03/075853 (2003-09-01), None
patent: WO2004/071449 (2004-08-01), None
patent: WO2004/071460 (2004-08-01), None
patent: WO2004/098512 (2004-11-01), None
patent: WO2004/098516 (2004-11-01), None
Baba et al., A Small-Molecule, Nonpeptide CCR5 Antagonist With Hihgly Potent and Selective Anti-HIV-1 Activity, Proc. Natl. Acad. Sci., May 1999, vol. 96, pp. 6598-5703.
Forbes, et al., CCR2B Receptor Antagonists: Conversion of a Weak HTS it to a Potent Lead Compound, Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, pp. 1803-1806.
Mirzadegan, et al. Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists, The Journal of Biological Chemistry, 2000, vol. 275 No. 33, pp. 25562-25571.
Cutrufo, et al., Effect of MEN 11467, a newty tachykinin NK1receptor antagonist, in acute rectocolitis induced by acetic acid in guinea-pigs, Eu. J. Pharm., 1999, vol. 374, No. 2, pp. 277-283.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cyclic derivatives as modulators of chemokine receptor activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic derivatives as modulators of chemokine receptor activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic derivatives as modulators of chemokine receptor activity will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4094893

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.