Cyclic derivatives as modulators of chemokine receptor activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S210010, C544S107000, C548S557000, C564S139000

Reexamination Certificate

active

10837179

ABSTRACT:
The present application describes modulators of MCP-1 of formula (I):or pharmaceutically acceptable salt forms thereof, useful for the prevention of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.

REFERENCES:
patent: 5700801 (1997-12-01), Pieper et al.
patent: 6011052 (2000-01-01), Padia et al.
patent: 6706712 (2004-03-01), Cherney
patent: 2003/0060459 (2003-03-01), Carter et al.
patent: 2003/0216434 (2003-11-01), Cherney
patent: 2004/0110736 (2004-06-01), Cherney
patent: 2004/0186143 (2004-09-01), Carter et al.
patent: 2004/0235835 (2004-11-01), Carter
patent: 2005/0043392 (2005-02-01), Carter
patent: 19607436 (1997-04-01), None
patent: 686629 (1995-12-01), None
patent: 2003183286 (2003-07-01), None
patent: WO97/44329 (1997-11-01), None
patent: WO98/06703 (1998-02-01), None
patent: WO99/07351 (1999-02-01), None
patent: WO99/07678 (1999-02-01), None
patent: WO99/25686 (1999-05-01), None
patent: WO99/40913 (1999-08-01), None
patent: WO99/40914 (1999-08-01), None
patent: WO99/46991 (1999-09-01), None
patent: WO 00/46196 (2000-08-01), None
patent: WO 00/69815 (2000-11-01), None
patent: WO 00/69820 (2000-11-01), None
patent: WO 01/74774 (2001-11-01), None
patent: WO 02/50019 (2002-06-01), None
patent: WO 02/060859 (2002-08-01), None
patent: WO 02/070523 (2002-09-01), None
patent: WO 02/074738 (2003-02-01), None
patent: WO 03/016302 (2003-02-01), None
patent: WO03022799 (2003-03-01), None
patent: WO 03075853 (2003-09-01), None
patent: WO 2004/005248 (2004-01-01), None
patent: WO 2004071449 (2004-08-01), None
patent: WO 2004071460 (2004-08-01), None
patent: WO 2004098512 (2004-11-01), None
Forbes, I.T. et al., “CCR2B Receptor Antagonists: Conversion of a Weak HTS Hit to a Potent Lead Compound”, Bioorganic & Medicinal Chemistry Letters, vol. 10, pp. 1803-1806 (2000).
Mirzadegan, T. et al., “Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists”, The Journal of Biological Chemistry, vol. 275, No. 33, pp. 25562-25571 (2000).
Baba, M. et al., “A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity”, Proc. Natl. Acad. Sci. USA, vol. 96, pp. 5698-5703 (1999).
U.S. Appl. No. 10/776,828, filed Feb. 11, 2004.
U.S. Appl. No. 10/776,586, filed Feb. 11, 2004.
U.S. Appl. No. 10/836,032, filed Apr. 29, 2004.
U.S. Appl. No. 10/922,406, Carter et al., filed Aug. 19, 2004.
U.S. Appl. No. 10/923,619, Carter et al., filed Aug. 19, 2004.
U.S. Appl. No. 10/923,538, Carter et al., filed Aug. 19, 2004.

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