Cyclic conjugated enediynes

Details Cyclic conjugated enediynes Cyclic conjugated enediynes

1988-06-30

1992-03-17

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

568700, 536 29, C07C 6902

Patent

active

050970623

ABSTRACT:
The synthesis of stable, ten-membered cyclic conjugated enediynes is described. Said compounds were successfully employed to cleave double-stranded DNA spontaneously at ambient temperatures.

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Kim, S. C., et al., Science 240, 405 (1988).

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