Cyclic compounds linked by a heterocyclic ring useful as inhibit

Details Cyclic compounds linked by a heterocyclic ring useful as inhibit Cyclic compounds linked by a heterocyclic ring useful as inhibit

1997-03-12

1998-12-15

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 2, 530317, A61K 3812, C07K 754

Patent

active

058496939

ABSTRACT:
This invention relates to novel cyclic compounds linked by a heterocyclic ring system, which are useful as antagonists of the platelet glycoprotein IIb/IIIa complex, to pharmaceutical compositions containing such cyclic compounds, and to methods of using these compounds for the inhibition of platelet aggregation.

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Cadroy et al. (1989) J. Clin. Invest. 84: 939-944.
Phillips et al. (1991) Cell 65: 359-362.
Burnier et al., in Peptides, Chemistry and Biology, Proc. 12th A.P.S., Jun. 16-21, 1991.

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