Cyclic compounds

Details Cyclic compounds Cyclic compounds

2011-03-01

2011-03-01

Habte, Kahsay T (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S280000

Reexamination Certificate

active

07897607

ABSTRACT:
There is provided a CRF receptor antagonist comprising a compound of the formula (I):in-line-formulae description="In-line Formulae" end="lead"?A-W—Ar  (I)in-line-formulae description="In-line Formulae" end="tail"?wherein, A is a group represented by the formula (A1) or (A2):(wherein, ring Aa is a 5- or 6-membered ring which may be further substituted; ring Ab is a 5- or 6-membered ring which may be further substituted; ring Ac is a 5- or 6-membered ring which may be substituted; R1is optionally substituted alkyl, substituted amino, substituted hydroxy, etc.; X is carbonyl, —O—, —S—, etc.; Y1, Y2and Q are independently optionally substituted carbon or nitrogen; is a single or double bond);W is a bond, optionally substituted methylene, optionally substituted imino, —O—, —S—, etc.; Ar is optionally substituted aryl or optionally substituted heteroaryl; or a salt thereof or a prodrug thereof.

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