Cyclic azaaliphatic compounds with a nitroxy function, processes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514330, 514408, 514423, 514428, 546242, 546245, 546246, 548517, 548538, 548566, 548570, A61K 31445, C07D21128, C07D20708

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active

052800318

ABSTRACT:
The present invention provides anti-angina pharmaceutical compositions containing at least one compound of the formula: ##STR1## wherein n is 1 or 2, R is a hydrogen atom or an H--(C.sub.1 -C.sub.8)-alkylene, hydroxy-(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N--(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N--(C.sub.1 -C.sub.8)-alkylene-CO--, R.sup.1 R.sup.2 N--CO--NR.sup.3 --(C.sub.1 -C.sub.8)-alkylene or R.sup.1 R.sup.2 N--CO-- radical, A is a valency bond or an --NR.sup.4 --CO-- or --CO-- NR.sup.4 -- radical, R.sup.4 is a hydrogen atom or a straight-chained or branched, saturated or unsaturated or cyclic alkyl radical containing up to 6 carbon atoms and B is a valency bond or a straight-chained or branched alkylene chain containing up to 8 carbon atoms, in which a --CH.sub.2 -- group can be replaced by a cycloalkylene radical containing 3 to 7 carbon atoms.

REFERENCES:
patent: 3869463 (1975-03-01), Archibald
patent: 4405334 (1983-09-01), Seemuth
patent: 4801596 (1989-01-01), Simon
Chemical Abstracts, vol. 106, No. 186566r (1988), pp. 688-689.
Physical Organic Chemistry, vol. 97, 109228j (1982), p. 539.
Chemical Abstracts, vol. 103, 141568y (1985), p. 686.
Chemical Abstracts, vol. 104, 88398k (1986), p. 644.

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