Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-05-14
1994-01-18
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514330, 514408, 514423, 514428, 546242, 546245, 546246, 548517, 548538, 548566, 548570, A61K 31445, C07D21128, C07D20708
Patent
active
052800318
ABSTRACT:
The present invention provides anti-angina pharmaceutical compositions containing at least one compound of the formula: ##STR1## wherein n is 1 or 2, R is a hydrogen atom or an H--(C.sub.1 -C.sub.8)-alkylene, hydroxy-(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N--(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N--(C.sub.1 -C.sub.8)-alkylene-CO--, R.sup.1 R.sup.2 N--CO--NR.sup.3 --(C.sub.1 -C.sub.8)-alkylene or R.sup.1 R.sup.2 N--CO-- radical, A is a valency bond or an --NR.sup.4 --CO-- or --CO-- NR.sup.4 -- radical, R.sup.4 is a hydrogen atom or a straight-chained or branched, saturated or unsaturated or cyclic alkyl radical containing up to 6 carbon atoms and B is a valency bond or a straight-chained or branched alkylene chain containing up to 8 carbon atoms, in which a --CH.sub.2 -- group can be replaced by a cycloalkylene radical containing 3 to 7 carbon atoms.
REFERENCES:
patent: 3869463 (1975-03-01), Archibald
patent: 4405334 (1983-09-01), Seemuth
patent: 4801596 (1989-01-01), Simon
Chemical Abstracts, vol. 106, No. 186566r (1988), pp. 688-689.
Physical Organic Chemistry, vol. 97, 109228j (1982), p. 539.
Chemical Abstracts, vol. 103, 141568y (1985), p. 686.
Chemical Abstracts, vol. 104, 88398k (1986), p. 644.
Bartsch Wolfgang
Michel Helmut
Schultz Michael
Simon Herbert
Boehringer Mannheim GmbH
Chang Celia
Ivy C. Warren
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