Cyclic azaaliphatic compounds with a nitroxy function, processes

Details Cyclic azaaliphatic compounds with a nitroxy function, processes Cyclic azaaliphatic compounds with a nitroxy function, processes

1989-10-20

1991-07-09

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514428, 546242, 548570, A61K 31445, A61K 3140, C07D295033

Patent

active

050306413

ABSTRACT:
The present invention provides anti-angina pharmaceutical compositions containing at least one compound of the formula: ##STR1## wherein n is 1 or 2, R is a hydrogen atom or an H-(C.sub.1 -C.sub.8)-alkylene, hydroxy-(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N-(C.sub.1 -C.sub.8)-alkylene, R.sup.1 R.sup.2 N-(C.sub.1 -C.sub.8)-alkylene-CO--, R.sup.1 R.sup.2 N-CO-NR.sup.3 -(C.sub.1 -C.sub.8)-alkylene or R.sup.1 R.sup.2 N-CO-- radical, A is a valency bond or an --NR.sup.4 --CO-- or --CO--NR.sup.4 -- radical, R.sup.4 is a hydrogen atom or a straight-chained or branched, saturated or unsaturated of cyclic alkyl radical containing up to 6 carbon atoms and B is a valency bond or a straight-chained or branched alkylene chain containing up to 8 carbon atoms, in which a --CH.sub.2 -- group can be replaced by a cycloalkylene radical containing 3 to 7 carbon atoms.

REFERENCES:
patent: 3869463 (1975-03-01), Archibald
Chemical Abstracts, vol. 106, No. 21 (1988), pp. 688-689.
Physical Organic Chemistry, vol. 97, No. 13 (1982), p. 539.
Chemical Abstracts, vol. 103, No. 17 (1985), p. 686.
Chemical Abstracts, vol. 104, No. 11 (1986), p. 644.

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