Cyclic anthranilic acid derivatives

Details Cyclic anthranilic acid derivatives Cyclic anthranilic acid derivatives

1992-08-14

1994-01-25

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546165, 546166, C07D21512, C07D21514, A61K 3147

Patent

active

052816001

ABSTRACT:
An antirheumatoid pharmaceutical composition containing a cyclic anthranilic acid derivative of the following formula, ##STR1## wherein R.sup.1, and R.sup.2 and R.sup.3 each independently indicate a hydrogen atom, halogen atom, lower alkyl group having 1 to 3 carbon atoms, lower alkoxy group having 1 to 3 carbon atoms, amino group, nitro group, hydroxy group, sulfonamide group, trifluoromethyl group, cyano group, carboxyl group, carbamoyl group, acetyl group, benzoylmethyl group which may be substituted, methylthio group, phenylethynyl group which may be substituted, ethynyl group which may be substituted, alkanoylamino group having 1 to 3 carbon atoms, benzoylamino group which may be substituted, alkylsulfonylamino group having 1 to 3 carbon atoms or phenylsulfonylamino group which may be substituted; R.sup.4 and R.sup.5 each independently indicate a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms, cyano group, carboxyl group, hydroxymethyl group, phenyl group which may be substituted or benzyl group; R.sup.6 indicates a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms or benzyl group; X is a methylene; the acid or alkali salts thereof and an insert, pharamaceutically acceptable carrier.

REFERENCES:
patent: 4843082 (1989-06-01), Biller et al.
Ono et al. Chem. Abstracts, vol. 111, No. 7, 57743j (1989).
Ziegler et al. Chem. Abstracts vol. 60; 15827h (1964).
Gridneva et al. Chem. Abstracts vol. 110, No. 19; 165944p (1989).
Gracheva et al. Chem Abstracts vol. 108, No. 23; 20451b (1988), and vol. 110 No. 3; 23698n (1988).
Coppola, G. Chem. Abstracts vol. 90, No. 3; 22931q (1979).

Affiliated with

Also associated with

Rating

Cyclic anthranilic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic anthranilic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic anthranilic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-727880