Cyclic analogs of atrial natriuretic peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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530325, 530326, 530327, 530328, C07K 706, C07K 708, C07K 710, A61K 3702

Patent

active

049354922

ABSTRACT:
Compounds and compositions comprising cyclic synthetic analogs of Atrial Natriuretic Peptides are provided, together with methods for their production and use as natriuretics, diuretics and/or vasodilators, or as intermediates for or modulators of such useful compounds or of native Atrial Natriuretic Peptides.

REFERENCES:
patent: 4496544 (1985-01-01), Needleman
patent: 4757048 (1988-07-01), Lewicki et al.

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