Cyclic analogs of alpha-MSH fragments

Details Cyclic analogs of alpha-MSH fragments Cyclic analogs of alpha-MSH fragments

1994-12-06

1997-10-07

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530317, A61K 3800, A61K 3802, C07K 500, C07K 700

Patent

active

056748396

ABSTRACT:
Cyclic Alpha-MSH fragment analogues of Ac-Nle.sup.4 -Glu.sup.5 -His.sup.6 -D-Phe.sup.7 -Arg.sup.8 -Try.sup.9 -Gly.sup.10 -NH.sub.2. The method of stimulating melanocytes by the transdermal application of these biologically-active analogues and compositions comprising these analogues for use in the method are disclosed.

REFERENCES:
patent: 4485039 (1984-11-01), Hruby et al.
Al-Obeidi et al., J. Med. Chem., vol. 32, pp. 2555-2561, No. 12, 1989.
Hruby, Life Sciences, vol. 31, pp. 189-199, 1982.

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