Cyclic amine compounds and pharmaceutical use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544353, 546206, 546193, 546194, 546141, 546149, 546203, 546205, 514318, 514325, A61K 31445, C07D24136, C07D21106, C07D21718

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active

051009013

ABSTRACT:
A cyclic amine compound is defined by the formula: ##STR1## in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is --(CHR22) r--, R22 being H or methyl, --CO-- (CHR22)r--, .dbd.(CH--CH.dbd.CH)b--, .dbd.CH--(CH2)c-- or .dbd.(CH--CH)d.dbd. and the ring including T and Q is piperidine. The compound is useful to treat senile dementia.

REFERENCES:
CA 110:173102c Preparation . . . Inhibitors, Sugimoto et al. p. 763, Dec. 1988.
CA 111:232532p Synthesis of . . . Hydrochloride, Iimura et al, 1989.

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