Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-06-14
1994-03-08
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544 92, 544 93, 544 94, C07D26526, C07D26518, A61K 31535
Patent
active
052927350
ABSTRACT:
The cyclic amide derivative is defined by the formula (I) or a salt thereof: R1--(CH2)n-z in which R1 is a group derived from a cyclic amide compound, substituted or unsubstituted, n is zero or an integer of 1 to 10 and Z is ##STR1## R2 being an aryl, a substituted aryl, a cycloalkyl or a heterocyclic group, m being an integer of 1 to 6, R3 being hydrogen or a lower alkyl, R4 being an aryl or a substituted aryl, a cycloalkyl or a heterocyclic group, p being an integer of 1 to 6, provided that the cyclic amide compound is quinazoline-on or quinazoline-dion, R2 and R4 are neither aryl nor substituted aryl. The cyclic amide compound is pharmacologically effective to prevent and treat diseases due to insufficiency of the central choline functions.
REFERENCES:
patent: 3494932 (1970-02-01), Brabander
patent: 4066772 (1978-01-01), Van den Berk et al.
patent: 4137318 (1979-01-01), Eberlein et al.
patent: 4446141 (1984-05-01), Nakamizo et al.
patent: 4490369 (1984-12-01), Reiffen et al.
patent: 4505911 (1985-03-01), Dolak et al.
patent: 4604388 (1986-08-01), Leonard et al.
patent: 4737495 (1988-04-01), Bomhard et al.
patent: 4871735 (1989-10-01), Heider et al.
patent: 4912115 (1990-03-01), Bomhard et al.
patent: 5034401 (1991-07-01), Frost et al.
Stamm et al., Chemical Abstracts, vol. 61, entry 12012d (1964).
J. Med. Chem. vol. 32, 1989, pp. 1921-1926: R. A. Glennon et al.; N-phthalimidoalkyl Derivatives of Serotonergic Agents.
Patent Abstracts of Japan, vol. 15, No. 104 (C-814)(4632), 1991 & JP-A/32155.
Chem. Pharm. Bull., vol. 35, No. 9, 1987 pp. 3558-3567: T. Takeda et al.: Synthesis and Properties of Deoxyoligonucleotides Containing Putrescinylthymine.
Chem. Pharm. Bull., vol. 34, No. 3, 1986, pp. 1032-1038: M. Niitsu et al.: Synthesis of a Series of Linear Pentaamines with Three and Four Methylene Chain Intervals.
Helvetica Chimica Acta, vol. 64, No. 40, Fasc. 2, 1981, pp. 399-406.
J. Heterocyclic Chem., vol. 20, No. 5, 1983, pp. 1271-1275; R. Granados et al.
Patent Abstracts of Japan, vol. 14, No. 435 (C-760) (4378, 1990) & JP-A 2169569 Eisai Co., Ltd.
Iimura Youichi
Karibe Norio
Kosasa Takashi
Nagato Satoshi
Ogura Hiroo
Eisai Co. Ltd.
Ford John M.
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