Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-05-17
1977-10-25
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
26032615, 260465E, 260465F, 424274, A61K 31275, C07C12180
Patent
active
040556581
ABSTRACT:
Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-[1-hydroxy-2-[(1,1-dimethyl-2-phenylethyl)amino]ethyl]-benzene acetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.
REFERENCES:
patent: 3644353 (1972-02-01), Lunts et al.
patent: 3701808 (1972-10-01), Hartley et al.
patent: 3718744 (1973-02-01), Kaiser et al.
patent: 3801631 (1974-04-01), Comer et al.
Kreighbaum William E.
Matier William L.
Roth Herbert R.
Brust Joseph Paul
Carnahan R. E.
Mead Johnson & Company
Uloth R. H.
Whittenbaugh Robert C.
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