Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-09-11
2010-12-28
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S228200, C514S253050, C544S061000, C544S121000, C544S128000, C544S363000
Reexamination Certificate
active
07858620
ABSTRACT:
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides a process for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
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Siuciak et al. Expert Opin.Drug Discov. vol. 2(7), p. 1001-1009 (2007).
Jan Kehler, et al. The potential therapeutic use of phosphodiesterase 10 inhibitors. Expert Opinion in Therapeutic Patents, 2007, 17(2), 147-158.
Kehler Jan
Langgaard Morten
Nielsen Jacob
Bernhardt Emily
H. Lundbeck A/S
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