Cyanoimidazole nucleoside derivatives

Details Cyanoimidazole nucleoside derivatives Cyanoimidazole nucleoside derivatives

1985-03-08

1988-03-01

Brown, J. R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 22, C07H 19067, C07H 19052

Patent

active

047287292

ABSTRACT:
A novel cyanoimidazole nucleoside and derivative thereof, particularly 4-cyanoimidazolium-5-olate nucleoside and acyl derivatives thereof, and pharmaceutically acceptable salts thereof which are useful as antitumor agents and immunosuppressants, are prepared by dehydrating carboxamide derivatives of the formula: ##STR1## wherein R is an acyl group, and then, if desired, deacylating.

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