Cyanocyclopenta[c]pyrrole derivatives

Details Cyanocyclopenta[c]pyrrole derivatives Cyanocyclopenta[c]pyrrole derivatives

1977-10-04

1979-02-20

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D41307

Patent

active

041408543

ABSTRACT:
2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as antisecretory and anti-ulcer agents are prepared by hydrolysis or thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.

REFERENCES:
chem. Abstracts, vol. 82, (1975), No. 43169x.

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