Cyanocarboxamidines and quinazoline process

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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260239BC, 2602433, 260302H, 260307A, 2603323R, 2603477, 544291, 544367, 544369, C07D23995

Patent

active

041385616

ABSTRACT:
Novel cyanocarboxamidines are disclosed. The new cyanocarboxamidines are particularly valuable as intermediates in the preparation of antihypertensive 4-amino-2-(4-substituted-piperazin-1-yl)-quinazolines.

REFERENCES:
patent: 3935213 (1973-12-01), Hess
Curd et al., J. Chem. Soc., 1759-1766 (1948).
Budesinsky et al., Coll. Czech. Chem. Commun., 37, 2779-2785 (1972).
Ried et al., Chem. Ber., 109, 2706-2715 (1976).

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