Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-03-01
2011-03-01
Henley, III, Raymond J (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S302000, C514S361000, C514S367000, C514S376000
Reexamination Certificate
active
07897615
ABSTRACT:
The present invention provides previous methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
REFERENCES:
patent: 3728455 (1973-04-01), Kupfer et al.
patent: 5177097 (1993-01-01), Poss
patent: 5190942 (1993-03-01), Poss
patent: 5208234 (1993-05-01), Poss
patent: 5208235 (1993-05-01), Poss
patent: 5212177 (1993-05-01), Poss
patent: 5225408 (1993-07-01), Weller
patent: 5256695 (1993-10-01), Poss
patent: 5374615 (1994-12-01), Poss
patent: 5378704 (1995-01-01), Weller
patent: 5428033 (1995-06-01), Belley
patent: 5470975 (1995-11-01), Atwal
patent: 5512681 (1996-04-01), Boswell
patent: 5519143 (1996-05-01), Harris
patent: 5534347 (1996-07-01), Chen
patent: 5736297 (1998-04-01), Roeschert
patent: 5895771 (1999-04-01), Epstein
patent: 5977413 (1999-11-01), Tomaru
patent: 7285562 (2007-10-01), Kafka et al.
patent: 197 16 231 (1998-10-01), None
patent: 197 22 952 (1998-10-01), None
patent: 0 144 101 (1985-06-01), None
patent: 0 296 722 (1988-10-01), None
patent: 0 481 448 (1992-04-01), None
patent: 0 547 442 (1993-06-01), None
patent: 0 556 060 (1993-08-01), None
patent: 0 733 366 (1996-09-01), None
patent: 0 733 614 (1998-05-01), None
patent: 0 916 352 (1998-12-01), None
patent: 2 784 114 (2000-04-01), None
patent: 2 321 244 (1998-07-01), None
patent: 2 337 701 (1999-01-01), None
patent: 05 124925 (1993-09-01), None
patent: 08 311036 (1996-11-01), None
patent: 09 012585 (1997-01-01), None
patent: 1743153 (1995-02-01), None
patent: 1825496 (1994-12-01), None
patent: WO 87/05297 (1987-09-01), None
patent: WO 91/00277 (1991-01-01), None
patent: WO 91/00281 (1991-01-01), None
patent: WO 92/00067 (1992-01-01), None
patent: WO 93/21158 (1993-10-01), None
patent: WO 93/21168 (1993-10-01), None
patent: WO 94/10692 (1994-05-01), None
patent: WO 94/14453 (1994-07-01), None
patent: WO 94/15932 (1994-07-01), None
patent: WO 94/18606 (1994-08-01), None
patent: WO 95/35312 (1995-10-01), None
patent: WO 95/29904 (1995-11-01), None
patent: WO 95/35311 (1995-12-01), None
patent: WO 95/35313 (1995-12-01), None
patent: WO 96/13491 (1996-05-01), None
patent: WO 96/13500 (1996-05-01), None
patent: WO 98/25931 (1998-06-01), None
patent: WO 99/12938 (1999-03-01), None
patent: WO 99/47497 (1999-09-01), None
patent: WO 99/65884 (1999-12-01), None
patent: WO 00/09710 (2000-02-01), None
patent: WO 00/20472 (2000-04-01), None
patent: WO 00/34344 (2000-06-01), None
patent: WO 00/37422 (2000-06-01), None
patent: WO 00/46203 (2000-08-01), None
patent: WO 00/54759 (2000-09-01), None
patent: WO 00/56710 (2000-09-01), None
patent: WO 00/69810 (2000-11-01), None
patent: WO 01/03705 (2001-01-01), None
patent: WO 02/058690 (2002-08-01), None
patent: WO 02/058698 (2002-08-01), None
patent: WO 02/064136 (2002-08-01), None
Deems et al., The American Physiological Society, 1998, R524-R528, vol. 274.
Dyck et al., The American Physiological Society, 1998, H2122-2129, vol. 275.
FitzPatrick et al., Am. J. Hum. Genet. 1999, 318-326, vol. 65.
Fraser et al., Febs Letters, 1999, 69-74, vol. 446.
Gao et al., Journal Lipid Research, 1999, 178-182, vol. 40.
Hearse, Metabolic Approaches to Ischaemic Heart Disease and it Management, Science Press, London, UK.
Jang et al., The Journal of Biological Chemistry, 1989, 3500-3505, vol. 264, No. 6.
Kantor et al., Circulation Research, 2008, 580-588, vol. 86.
Kennedy et al., Biochemical Pharmacology, 1996, 273-280, vol. 52.
Kim and Kolattukudy, Archives of Biochemistry and Biophysics, 1978, 585-597, vol. 190, No. 2.
Kim and Kolattukudy, Archives of Biochemistry and Biophysics, 1978, 234-246, vol. 190, No. 1.
Kim and Kolattukudy, Biochemica et Biophysica Acta, 1978, 187-196, vol. 531.
Loftus et al., Science, 2000, 237-238, vol. 288.
McCormack et al., Genet. Pharmac., 1998, 639-645, vol. 30, No. 5).
McGarry and Brown, Eur. J. Biochem., 1997, 1-14, vol. 244.
McNeill, Measurement of Cardiovascular Func., CRC Press, Boca Raton, USA.
Pepine et al., The American Journal of Cardiology, 1999, 46-50, vol. 84.
Pizer et al., Cancer Research, 2000, 213-218, vol. 60.
Prentki et al., Diabetes, 1996, 273-283, vol. 45.
Randle et al., Lancet, 1963, 785-789, vol. 1.
Sacksteder et al., The Journal of Biological Chemistry, 1999, 24461-24468, vol. 274, No. 35.
Voilley et al., Biochem. J., 1999, 213-217, vol. 340.
Wargovich et al., Am J Cardiol, 1988, 65-70, vol. 61.
Zammit, Biochemical Society, 1999, 505-515, vol. 343.
Database Biosis ′Online!, Biosciences Information Service, 1976, Database accession No. PREV197763044218, 002207355.
Chemical Abstracts, 1969, vol. 71, No. 23, Columbus, OH, US, XP002207359.
“Fluka Chemika-Biochemika” Fluka Chemie AG, Buchs (CH), XP002230053, 1995, 331.
Abo-Hashema et al., Biochemistry, 1999, 15840-15847, vol. 38.
Abo-Hashema et al., Journal of Biological Chemistry, 1999, 35577-35582, vol. 274, No. 50.
Alam and Saggerson, “Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle” Biochem J. 334:233-241 (1998).
An et al., Journal of Biochemistry and Molecular Biology, 1999, 414-418, vol. 32, No. 4.
Anderson, Current Pharmaceutical Design, 1998, 1-16, vol. 4, No. 1.
Buckner, et al., Archives of Biochemistry Biophysics, 1976, 539-551, vol. 177.
Cecil, Textbook of Medicine, 21sted., vol. 1, published 2000 by W.B. Saunders Company (PA), pp. 1060-1074.
Dyck Jason R.
Kafka Mark D.
Lopaschuk Gary D.
Russell Anna
Wilson Mark E.
Chugai Sciyaku Kabushiki Kaisha
Fish & Richardson P.C.
Henley, III Raymond J
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