Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles
Patent
1990-01-29
1991-02-19
Brust, Joseph Paul
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitriles
558351, 558352, C07C25308, C07C25310
Patent
active
049945963
ABSTRACT:
1-Cyano-1-(4-alkylphenyl)alkenes having utility as chemical intermediates, especially in the preparation of ibuprofen and related pharmaceuticals, are prepared by reacting an alkylbenzene with an alkali metal cyanide and an acid halide in the presence of aluminum chloride.
REFERENCES:
patent: 3228831 (1966-01-01), Nicholson et al.
patent: 4536343 (1985-08-01), Ramachandran
patent: 4581176 (1986-08-01), Davidson
Noller, "Chemistry of Organic Compounds," 3rd Ed., (1965), p. 585, W. B. Saunders Co., Phila. & London.
Brust Joseph Paul
Ethyl Corporation
Hammond Richard J.
Hogan Patricia J.
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