Cyanine compounds and their application as quenching compounds

Details Cyanine compounds and their application as quenching compounds Cyanine compounds and their application as quenching compounds

2007-09-18

2007-09-18

Anderson, Rebecca (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S159000, C548S465000

Reexamination Certificate

active

10916822

ABSTRACT:
The present invention provides methods and non-fluorescent carbocyanine quencher compounds having the general formula:Wherein the A moiety is a substituted pyridinium, unsubstituted pyridinium, substituted quinolinium, unsubstituted quinolinium, substituted benzazolium, unsubstituted benzazolium, substituted indolinium, or unsubstituted indolinium. The invention further provides luminescent donor molecule-quencher pairs and luminescent donor molecule-quencher-luminescent acceptor molecule conjugates wherein the quencher is a cyanine compound of the present invention. The energy transfer pairs are used to detect an analyte of interest in a sample.

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