Cyanide-free hemoglobin reagent

Details Cyanide-free hemoglobin reagent Cyanide-free hemoglobin reagent

1994-02-07

1995-11-21

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Hemoglobin, myoglobin, or occult blood

436 63, 436166, 356 40, G01N 3372

Patent

active

054686407

ABSTRACT:
A novel method and reagent useful therein are cyanide-free and capable of providing a rapid indication, e.g., less than 30 seconds, of total hemoglobin in a blood sample, so as to find particular application in automated hematological instrumentation. The novel reagent comprises an ionic surfactant, a pH of at least about 11.3 and is free of ionic cyanide. The ionic surfactant itself can impart the required pH or a strong base independent of such surfactant may be included.

REFERENCES:
patent: 4007008 (1977-02-01), Becker et al.
patent: 4185964 (1980-01-01), Lancaster
patent: 4238196 (1980-12-01), Acuff et al.
patent: 4853338 (1989-08-01), Benezra et al.
Oshino et al. "A New Hemoglobin Determination Method. Attempted Determination of Hemoglobin Using SLS" Rinsho Byorei 29(2): 203-9 (1981).

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