Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood
Patent
1997-05-13
1999-01-12
Wallenhorst, Maureen M.
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
436 8, 436 17, 436 18, 436 63, 436175, 435 2, 2524081, G01N 3372
Patent
active
058587942
ABSTRACT:
The invention describes an improved stable reagent composition and method for the determination of hemoglobin (Hb) using whole blood samples and automated hematology analyzers. The Hb reagent contains an inorganic cyanide salt, at least one surfactant and a base and has a final pH of about 10.0 to about 11.2, preferably about 10.4 to about 11.2 or less and more preferably about 10.8 to about 11.2 or less. This reagent is intended for use as a universal Hb determination reagent for all of the instruments in the aforementioned series and will provide accurate and precise results without accompanying interference from elevated numbers of white blood cells, especially as found in abnormal blood specimens, and without system-to-system variation in the results obtained.
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Bayer Corporation
Wallenhorst Maureen M.
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